Version 5.4
Mus musculus Protein: Pop4
Summary
InnateDB Protein IDBP-175624.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pop4
Protein Name processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)
Synonyms 1110023P21Rik; Rpp29;
Species Mus musculus
Ensembl Protein ENSMUSP00000032585
InnateDB Gene IDBG-175622 (Pop4)
Protein Structure
UniProt Annotation
Function Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleolus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004526 ribonuclease P activity
GO:0004540 ribonuclease activity
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
GO:0006379 mRNA cleavage
GO:0008033 tRNA processing
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0000172 ribonuclease MRP complex
GO:0005655 nucleolar ribonuclease P complex
GO:0030677 ribonuclease P complex
Protein Structure and Domains
PDB ID MGI:1913411
InterPro IPR002730 Ribonuclease P/MRP, subunit p29
IPR016848 Ribonuclease P/MRP, p29 subunit
IPR023534 Rof/RNase P-like
PFAM PF01868
PRINTS
PIRSF PIRSF027081
SMART SM00538
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CR08
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 66161
UniGene Mm.406016
RefSeq NP_079666
MGI ID
MGI Symbol Pop4
OMIM
CCDS CCDS39915
HPRD
IMGT
EMBL AK002855 AK003293 AK150459 AK152948 BC011465
GenPept AAH11465 BAB22410 BAB22696 BAE29579 BAE31617

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca