Version 5.4
Mus musculus Protein: Nxt2
Summary
InnateDB Protein IDBP-176133.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nxt2
Protein Name nuclear transport factor 2-like export factor 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000048221
InnateDB Gene IDBG-176131 (Nxt2)
Protein Structure
UniProt Annotation
Function Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0008150 biological_process
GO:0015031 protein transport
GO:0051028 mRNA transport
Cellular Component
GO:0005575 cellular_component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2147914
InterPro IPR002075 Nuclear transport factor 2
IPR018222 Nuclear transport factor 2, eukaryote
PFAM PF02136
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UNA4
PhosphoSite PhosphoSite-Q3UNA4
TrEMBL
UniProt Splice Variant
Entrez Gene 237082
UniGene Mm.41899
RefSeq NP_001154902
MGI ID
MGI Symbol Nxt2
OMIM
CCDS CCDS41155
HPRD
IMGT
EMBL AK032102 AK144349 AL731672 BC068166 BC094570 BC118503 CH466610
GenPept AAH68166 AAH94570 AAI18504 BAC27701 BAE25843 CAM15877 CAM15878 CAM15879 EDL14753 EDL14754

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca