InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Add3

Summary

InnateDB Protein

IDBP-176328.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Add3

Protein Name

adducin 3 (gamma)

Synonyms

AI463285; R75380;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025999

InnateDB Gene

IDBG-176324 (Add3)

Protein Structure

UniProt Annotation

Function

Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.

Subcellular Localization

Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005198	structural molecule activity
GO:0005516	calmodulin binding

Biological Process

Cellular Component

GO:0000794	condensed nuclear chromosome
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0005911	cell-cell junction
GO:0005938	cell cortex
GO:0016020	membrane