InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Igtp

Summary

InnateDB Protein

IDBP-176363.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Igtp

Protein Name

interferon gamma induced GTPase

Synonyms

AW558444; Irgm3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000047356

InnateDB Gene

IDBG-263693 (Igtp)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	3 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0016817	hydrolase activity, acting on acid anhydrides

Biological Process

GO:0006184	GTP catabolic process
GO:0035458	cellular response to interferon-beta
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005829	cytosol
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:107729

InterPro

IPR007743 Interferon-inducible GTPase
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF05049

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-NP_061208

TrEMBL

Q9DCE9

UniProt Splice Variant

Entrez Gene

16145

UniGene

Mm.487666

RefSeq

NP_061208

MGI ID

MGI Symbol

Igtp

OMIM

CCDS

CCDS24725

HPRD

IMGT

EMBL

AK002843 AK149817 AK151779 AK151860 AK152483 AK169307 AL928857 FR734032

GenPept

BAB22400 BAE29102 BAE30684 BAE30749 BAE31255 BAE41062 CBY65995