Version 5.4
Mus musculus Protein: Lmnb2
Summary
InnateDB Protein IDBP-176484.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lmnb2
Protein Name lamin B2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000057291
InnateDB Gene IDBG-176482 (Lmnb2)
Protein Structure
UniProt Annotation
Function Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Subcellular Localization Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.
Disease Associations
Tissue Specificity Isoform B3 is germ cell specific.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005637 nuclear inner membrane
GO:0005638 lamin filament
GO:0005882 intermediate filament
Protein Structure and Domains
PDB ID MGI:96796
InterPro IPR001322 Lamin Tail Domain
IPR001664 Intermediate filament protein
PFAM PF00932
PF00038
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P21619
PhosphoSite PhosphoSite-P21619
TrEMBL
UniProt Splice Variant
Entrez Gene 16907
UniGene Mm.7362
RefSeq
MGI ID
MGI Symbol Lmnb2
OMIM
CCDS
HPRD
IMGT
EMBL BC042430 BC051985 D13455 X54098
GenPept AAH42430 AAH51985 BAA02708 CAA38032

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca