Mus musculus Protein: Siglec5 | |||||||
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Summary | |||||||
InnateDB Protein | IDBP-176570.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Siglec5 | ||||||
Protein Name | sialic acid binding Ig-like lectin 5 | ||||||
Synonyms | |||||||
Species | Mus musculus | ||||||
Ensembl Protein | ENSMUSP00000012798 | ||||||
InnateDB Gene | IDBG-176568 (Siglec5) | ||||||
Protein Structure | |||||||
UniProt Annotation | |||||||
Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. | ||||||
Subcellular Localization | Membrane; Single-pass type I membrane protein. | ||||||
Disease Associations | |||||||
Tissue Specificity | Predominantly expressed by immature monocytic/myeloid lineage cells in bone marrow. Also found at lower levels in mature neutrophils and monocytes. | ||||||
Comments | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||
PDB ID | MGI:2681107 | ||||||
InterPro |
IPR003598
Immunoglobulin subtype 2 IPR003599 Immunoglobulin subtype IPR007110 Immunoglobulin-like domain IPR013098 Immunoglobulin I-set IPR013106 Immunoglobulin V-set domain IPR013151 Immunoglobulin |
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PFAM |
PF07679
PF07686 PF00047 |
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PRINTS | |||||||
PIRSF | |||||||
SMART |
SM00408
SM00409 |
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TIGRFAMs | |||||||
Post-translational Modifications | |||||||
Modification | |||||||
Cross-References | |||||||
SwissProt | Q920G3 | ||||||
PhosphoSite | PhosphoSite-Q920G3 | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 233186 | ||||||
UniGene | Mm.412877 | ||||||
RefSeq | NP_663556 | ||||||
MGI ID | |||||||
MGI Symbol | Siglec5 | ||||||
OMIM | |||||||
CCDS | CCDS21167 | ||||||
HPRD | |||||||
IMGT | |||||||
EMBL | AF293371 | ||||||
GenPept | AAL11043 | ||||||