Version 5.4
Mus musculus Protein: Klk1b26
Summary
InnateDB Protein IDBP-177956.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klk1b26
Protein Name kallikrein 1-related petidase b26
Synonyms Egfbp-2; Egfbp2; Klk1b26; Klk26; mGk-13; mGK-26; mGK26; PRECE-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000047488
InnateDB Gene IDBG-177954 (Klk1b26)
Protein Structure
UniProt Annotation
Function Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.Prorenin-converting enzyme cleaves mouse REN-2 prorenin at a dibasic site to yield mature renin.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0008233 peptidase activity
Biological Process
GO:0002035 brain renin-angiotensin system
GO:0006508 proteolysis
GO:0031638 zymogen activation
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:891981
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P36369
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 16618
UniGene
RefSeq NP_034774
MGI ID
MGI Symbol Klk1b26
OMIM
CCDS CCDS39938
HPRD
IMGT
EMBL BC024688 BC138704 K01831 V00828 X63327
GenPept AAA37540 AAH24688 AAI38705 CAA24211 CAA44931

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca