InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gigyf2

Summary

InnateDB Protein

IDBP-178128.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gigyf2

Protein Name

GRB10 interacting GYF protein 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000027475

InnateDB Gene

IDBG-178126 (Gigyf2)

Protein Structure

UniProt Annotation

Function

May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling, including IGF1 and insulin receptors. {ECO:0000269PubMed:12771153}.

Subcellular Localization

Disease Associations

Tissue Specificity

Expressed in heart and liver, in kidney and brain as well as in testis. {ECO:0000269PubMed:12771153}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	35 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0007631	feeding behavior
GO:0008344	adult locomotory behavior
GO:0009791	post-embryonic development
GO:0017148	negative regulation of translation
GO:0021522	spinal cord motor neuron differentiation
GO:0031571	mitotic G1 DNA damage checkpoint
GO:0035264	multicellular organism growth
GO:0044267	cellular protein metabolic process
GO:0048009	insulin-like growth factor receptor signaling pathway
GO:0048873	homeostasis of number of cells within a tissue
GO:0050881	musculoskeletal movement
GO:0050885	neuromuscular process controlling balance