InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TALDO1

Summary

InnateDB Protein

IDBP-17876.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TALDO1

Protein Name

transaldolase 1

Synonyms

TAL; TAL-H; TALDOR; TALH;

Species

Homo sapiens

Ensembl Protein

ENSP00000321259

InnateDB Gene

IDBG-17874 (TALDO1)

Protein Structure

UniProt Annotation

Function

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

Subcellular Localization

Cytoplasm {ECO:0000305}.

Disease Associations

Transaldolase 1 deficiency (TALDO1 deficiency) [MIM:606003]: Results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris. {ECO:0000269PubMed:11283793}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.

Experimentally validated
Total	32 [view]
Protein-Protein	32 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004801	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0005999	xylulose biosynthetic process
GO:0006098	pentose-phosphate shunt
GO:0006112	energy reserve metabolic process
GO:0044281	small molecule metabolic process