InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cxcl5

Summary

InnateDB Protein

IDBP-178770.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cxcl5

Protein Name

chemokine (C-X-C motif) ligand 5

Synonyms

AMCF-II; ENA-78; GCP-2; LIX; Scyb5; Scyb6;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031318

InnateDB Gene

IDBG-178768 (Cxcl5)

Protein Structure

UniProt Annotation

Function

May participate in the recruitment of inflammatory cells by injured or infected tissue. GCP-2(1-78) and, more potent, GCP- 2(9-78) attract neutrophils and are involved in neutrophil activation. {ECO:0000269PubMed:10570306}.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008009	chemokine activity

Biological Process

GO:0001776	leukocyte homeostasis
GO:0006954	inflammatory response
GO:0006955	immune response
GO:0032496	response to lipopolysaccharide
GO:0032642	regulation of chemokine production
GO:0045087	innate immune response (InnateDB)
GO:0060326	cell chemotaxis
GO:0070951	regulation of neutrophil mediated killing of gram-negative bacterium