Version 5.4
Mus musculus Protein: Zkscan17
Summary
InnateDB Protein IDBP-178782.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zkscan17
Protein Name zinc finger with KRAB and SCAN domains 17
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000013262
InnateDB Gene IDBG-178780 (Zkscan17)
Protein Structure
UniProt Annotation
Function DNA-binding transcription factor that can both act as an activator and a repressor. {ECO:0000269PubMed:15169884, ECO:0000269PubMed:17521633}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00187, ECO:0000269PubMed:15169884, ECO:0000269PubMed:17521633}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043621 protein self-association
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0016604 nuclear body
Protein Structure and Domains
PDB ID MGI:2679270
InterPro IPR001909 Krueppel-associated box
IPR003309 Transcription regulator SCAN
IPR007087 Zinc finger, C2H2
IPR008916 Retrovirus capsid, C-terminal
IPR015880 Zinc finger, C2H2-like
PFAM PF01352
PF02023
PF00096
PRINTS
PIRSF
SMART SM00349
SM00431
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5SXI5
PhosphoSite PhosphoSite-Q5SXI5
TrEMBL
UniProt Splice Variant
Entrez Gene 268417
UniGene Mm.239793
RefSeq NP_766529
MGI ID
MGI Symbol Zkscan17
OMIM
CCDS CCDS24770
HPRD
IMGT
EMBL AK051711 AK139346 AK155196 AK155490 AK170924 AK170989 AK171190 AL592522 AY302242 BC040205
GenPept AAH40205 AAQ73562 BAC34730 BAE23969 BAE33110 BAE33290 BAE42117 BAE42163 BAE42300 CAI24553 CAI24554

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca