Version 5.4
Mus musculus Protein: Eif2b3
Summary
InnateDB Protein IDBP-179212.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Eif2b3
Protein Name eukaryotic translation initiation factor 2B, subunit 3
Synonyms 1190002P15Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000070334
InnateDB Gene IDBG-179210 (Eif2b3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0006413 translational initiation
GO:0009058 biosynthetic process
GO:0009408 response to heat
GO:0009749 response to glucose
GO:0014003 oligodendrocyte development
GO:0032057 negative regulation of translational initiation in response to stress
GO:0043087 regulation of GTPase activity
GO:0043434 response to peptide hormone
Cellular Component
GO:0005851 eukaryotic translation initiation factor 2B complex
Protein Structure and Domains
PDB ID MGI:1313286
InterPro IPR005835 Nucleotidyl transferase
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF00483
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B1AUN3
UniProt Splice Variant
Entrez Gene 108067
UniGene
RefSeq XP_006502712
MGI ID
MGI Symbol Eif2b3
OMIM
CCDS
HPRD
IMGT
EMBL AL671866 AL831772
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca