InnateDB Protein
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IDBP-179240.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Man1a2
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Protein Name
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mannosidase, alpha, class 1A, member 2
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Synonyms
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AI428775; AI528764; AI854422; Man1b; PCR2;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000008907
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InnateDB Gene
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IDBG-179238 (Man1a2)
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Protein Structure
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|
Function |
Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
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Subcellular Localization |
Golgi apparatus membrane; Single-pass type II membrane protein.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
2
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
5 [view]
|
|
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Molecular Function |
Accession |
GO Term |
GO:0004571
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mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
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GO:0005509
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calcium ion binding
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:104676
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InterPro |
IPR001382
Glycoside hydrolase, family 47
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PFAM |
PF01532
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PRINTS |
PR00747
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PIRSF |
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SMART |
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TIGRFAMs |
|
Modification |
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SwissProt |
P39098
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PhosphoSite |
PhosphoSite-P39098
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
17156
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UniGene |
Mm.401081
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RefSeq |
NP_034893
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MGI ID |
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MGI Symbol |
Man1a2
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OMIM |
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CCDS |
CCDS17676
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HPRD |
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IMGT |
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EMBL |
AF078083
AF078084
AF078085
AF078086
AF078087
AF078088
AF078089
AF078090
AF078091
AF078092
AF078093
AF078094
AF078095
AK013515
AK153336
AL645760
BC049121
BC068192
U03457
U03458
|
GenPept |
AAB60438
AAB60439
AAC34829
AAH49121
AAH68192
BAB28892
BAE31915
CAI26213
CAI26214
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