InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cxcr7

Summary

InnateDB Protein

IDBP-179971.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cxcr7

Protein Name

chemokine (C-X-C motif) receptor 7

Synonyms

AW541270; Cmkor1; CXC-R7; CXCR-7; Cxcr7; RDC-1; Rdc1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000069114

InnateDB Gene

IDBG-179969 (Cxcr7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0005044	scavenger receptor activity
GO:0005515	protein binding
GO:0015026	coreceptor activity
GO:0016494	C-X-C chemokine receptor activity
GO:0019958	C-X-C chemokine binding

Biological Process

GO:0001525	angiogenesis
GO:0001570	vasculogenesis
GO:0006935	chemotaxis
GO:0007155	cell adhesion
GO:0007186	G-protein coupled receptor signaling pathway
GO:0031623	receptor internalization
GO:0070098	chemokine-mediated signaling pathway
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Cellular Component

GO:0005768	endosome
GO:0005769	early endosome
GO:0005886	plasma membrane
GO:0005905	coated pit
GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0048471	perinuclear region of cytoplasm
GO:0055037	recycling endosome

Protein Structure and Domains

PDB ID

MGI:109562

InterPro

IPR000248 Angiotensin II receptor family
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001416 CXC chemokine receptor 7
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00241
PR00237
PR00646

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P56485