InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pfkm

Summary

InnateDB Protein

IDBP-179974.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pfkm

Protein Name

phosphofructokinase, muscle

Synonyms

AI131669; ATP-PFK; Pfk-4; PFK-A; PFK-M; Pfk4; Pfka; Pfkx;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000059801

InnateDB Gene

IDBG-179972 (Pfkm)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003872	6-phosphofructokinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008022	protein C-terminus binding
GO:0008443	phosphofructokinase activity
GO:0019900	kinase binding
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0046872	metal ion binding
GO:0070061	fructose binding

Biological Process

GO:0006002	fructose 6-phosphate metabolic process
GO:0006096	glycolytic process
GO:0032024	positive regulation of insulin secretion
GO:0042593	glucose homeostasis
GO:0046716	muscle cell cellular homeostasis
GO:0046835	carbohydrate phosphorylation
GO:0051259	protein oligomerization
GO:0061615	glycolytic process through fructose-6-phosphate

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005945	6-phosphofructokinase complex
GO:0016324	apical plasma membrane
GO:0070062	extracellular vesicular exosome
GO:0097228	sperm principal piece