InnateDB Protein
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IDBP-180322.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Chn1
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Protein Name
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chimerin (chimaerin) 1
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Synonyms
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0610007I19Rik; 0710001E19Rik; 1700112L09Rik; 2900046J01Rik; AI413815; ARHGAP2;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000070301
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InnateDB Gene
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IDBG-180318 (Chn1)
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Protein Structure
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Function |
GTPase-activating protein for p21-rac and a phorbol ester receptor. May play an important role in neuronal signal- transduction mechanisms (By similarity). Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance. {ECO:0000250, ECO:0000269PubMed:17785183}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
4
[view]
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Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
5 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1915674
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InterPro |
IPR000198
Rho GTPase-activating protein domain
IPR008936
Rho GTPase activation protein
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PFAM |
PF00620
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PRINTS |
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PIRSF |
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SMART |
SM00324
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-Q91V57
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TrEMBL |
A7VK14
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UniProt Splice Variant |
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Entrez Gene |
108699
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UniGene |
Mm.489675
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RefSeq |
NP_083992
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MGI ID |
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MGI Symbol |
Chn1
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OMIM |
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CCDS |
CCDS38145
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HPRD |
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IMGT |
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EMBL |
AB264774
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GenPept |
BAF80063
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