InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc6a2

Summary

InnateDB Protein

IDBP-180393.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc6a2

Protein Name

solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

Synonyms

NE-T; NET; Slc6a5;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000072709

InnateDB Gene

IDBG-180391 (Slc6a2)

Protein Structure

UniProt Annotation

Function

Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005328	neurotransmitter:sodium symporter activity
GO:0005333	norepinephrine transmembrane transporter activity
GO:0005515	protein binding
GO:0008504	monoamine transmembrane transporter activity
GO:0043014	alpha-tubulin binding
GO:0048487	beta-tubulin binding

Biological Process

GO:0006836	neurotransmitter transport
GO:0015844	monoamine transport
GO:0015874	norepinephrine transport
GO:0042493	response to drug
GO:0048265	response to pain
GO:0055085	transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0043005	neuron projection
GO:0045121	membrane raft