InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sycp1

Summary

InnateDB Protein

IDBP-180493.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sycp1

Protein Name

synaptonemal complex protein 1

Synonyms

SCP1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000029448

InnateDB Gene

IDBG-180491 (Sycp1)

Protein Structure

UniProt Annotation

Function

Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.

Subcellular Localization

Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Found only where the chromosome cores are synapsed. Its N-terminus is found towards the center of the synaptonemal complex while the C- terminus extends well into the lateral domain of the synaptonemal complex (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding

Biological Process

GO:0000711	meiotic DNA repair synthesis
GO:0007130	synaptonemal complex assembly
GO:0007283	spermatogenesis
GO:0032880	regulation of protein localization
GO:0035092	sperm chromatin condensation
GO:0051026	chiasma assembly
GO:0051878	lateral element assembly

Cellular Component

GO:0000795	synaptonemal complex
GO:0000800	lateral element
GO:0000801	central element
GO:0000802	transverse filament
GO:0001673	male germ cell nucleus
GO:0005654	nucleoplasm
GO:0005694	chromosome