InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bnip2

Summary

InnateDB Protein

IDBP-181775.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bnip2

Protein Name

BCL2/adenovirus E1B interacting protein 2

Synonyms

5730523P12Rik; BNIP2beta; Nip21;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034754

InnateDB Gene

IDBG-181773 (Bnip2)

Protein Structure

UniProt Annotation

Function

Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Localizes to the nuclear envelope region and to other cytoplasmic structures. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0001824	blastocyst development
GO:0006915	apoptotic process
GO:0043410	positive regulation of MAPK cascade
GO:0045666	positive regulation of neuron differentiation
GO:0051057	positive regulation of small GTPase mediated signal transduction
GO:0051146	striated muscle cell differentiation
GO:0051297	centrosome organization

Cellular Component

GO:0005635	nuclear envelope
GO:0005737	cytoplasm
GO:0005814	centriole
GO:0005829	cytosol
GO:0031616	spindle pole centrosome
GO:0043231	intracellular membrane-bounded organelle
GO:0048471	perinuclear region of cytoplasm