InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cnksr2

Summary

InnateDB Protein

IDBP-181960.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cnksr2

Protein Name

connector enhancer of kinase suppressor of Ras 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000026750

InnateDB Gene

IDBG-181958 (Cnksr2)

Protein Structure

UniProt Annotation

Function

May function as an adapter protein or regulator of Ras signaling pathways.

Subcellular Localization

Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0009966

regulation of signal transduction

Cellular Component

GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0043005	neuron projection
GO:0043025	neuronal cell body
GO:0045211	postsynaptic membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:2661175

InterPro

IPR001478 PDZ domain
IPR001660 Sterile alpha motif domain
IPR001849 Pleckstrin homology domain
IPR010599 Connector enhancer of kinase suppressor of ras 2
IPR011510 Sterile alpha motif, type 2
IPR013761 Sterile alpha motif/pointed domain
IPR019555 CRIC domain, Chordata
IPR021129 Sterile alpha motif, type 1

PFAM