InnateDB Protein
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IDBP-182167.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Tnfrsf13b
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Protein Name
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tumor necrosis factor receptor superfamily, member 13b
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Synonyms
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1200009E08Rik; Taci;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000098662
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InnateDB Gene
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IDBG-182161 (Tnfrsf13b)
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Protein Structure
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Function |
Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T- cell function and the regulation of humoral immunity (By similarity). {ECO:0000250}.
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Subcellular Localization |
Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated |
Total |
7
[view]
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Protein-Protein |
7
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
15 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1889411
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InterPro |
IPR015384
TACI, cysteine-rich domain
IPR022317
Tumour necrosis factor receptor 13B
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PFAM |
PF09305
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PRINTS |
PR01963
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9ET35
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PhosphoSite |
PhosphoSite-Q9ET35
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TrEMBL |
B1ATI4
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UniProt Splice Variant |
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Entrez Gene |
57916
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UniGene |
Mm.265915
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RefSeq |
NP_067324
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MGI ID |
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MGI Symbol |
Tnfrsf13b
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OMIM |
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CCDS |
CCDS24806
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HPRD |
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IMGT |
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EMBL |
AF257673
AK004668
AL646093
BC139392
BC139393
BC141867
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GenPept |
AAG00081
AAI39393
AAI39394
AAI41868
BAB23457
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