Mus musculus Protein: Agxt
Summary
InnateDB Protein IDBP-182615.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Agxt
Protein Name alanine-glyoxylate aminotransferase
Synonyms AGT; Agt1; Agxt1; SPT;
Species Mus musculus
Ensembl Protein ENSMUSP00000027491
InnateDB Gene IDBG-182613 (Agxt)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004760 serine-pyruvate transaminase activity
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0008453 alanine-glyoxylate transaminase activity
GO:0008483 transaminase activity
GO:0016597 amino acid binding
GO:0030170 pyridoxal phosphate binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006625 protein targeting to peroxisome
GO:0008152 metabolic process
GO:0009436 glyoxylate catabolic process
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate
GO:0019448 L-cysteine catabolic process
GO:0042853 L-alanine catabolic process
GO:0042866 pyruvate biosynthetic process
GO:0046487 glyoxylate metabolic process
GO:0046724 oxalic acid secretion
GO:0051384 response to glucocorticoid
GO:0051591 response to cAMP
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005777 peroxisome
GO:0005782 peroxisomal matrix
Protein Structure and Domains
PDB ID MGI:1329033
InterPro IPR000192 Aminotransferase, class V/Cysteine desulfurase
IPR015424 Pyridoxal phosphate-dependent transferase
PFAM PF00266
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O35423
PhosphoSite PhosphoSite-O35423
TrEMBL Q3UEN9
UniProt Splice Variant
Entrez Gene 11611
UniGene Mm.7457
RefSeq NP_057911
MGI ID 3KGX
MGI Symbol Agxt
OMIM
CCDS CCDS15184
HPRD
IMGT
EMBL AC110247 AF027730 AK149432 BC025799 CH466520
GenPept AAB82001 AAH25799 BAE28872 EDL39972