InnateDB Protein
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IDBP-183126.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ano7
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Protein Name
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anoctamin 7
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000050495
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InnateDB Gene
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IDBG-183124 (Ano7)
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Protein Structure
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Function |
Does not exhibit calcium-activated chloride channel (CaCC) activity. May play a role in cell-cell interactions (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Note=Concentrates at sites of cell-cell contact. Shows an intracellular localization. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Highly expressed in the stomach. {ECO:0000269PubMed:20056604}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
Accession |
GO Term |
GO:0005229
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intracellular calcium activated chloride channel activity
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GO:0017128
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phospholipid scramblase activity
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Biological Process |
GO:0006821
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chloride transport
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GO:0061589
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calcium activated phosphatidylserine scrambling
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GO:0061590
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calcium activated phosphatidylcholine scrambling
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GO:0061591
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calcium activated galactosylceramide scrambling
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GO:1902476
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chloride transmembrane transport
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Cellular Component |
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PDB ID |
MGI:3052714
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InterPro |
IPR007632
Anoctamin
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PFAM |
PF04547
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q14AT5
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PhosphoSite |
PhosphoSite-Q14AT5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
404545
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UniGene |
Mm.297411
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RefSeq |
NP_001258813
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MGI ID |
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MGI Symbol |
Ano7
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AC108412
AC124669
BC116706
BK004075
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GenPept |
AAI16707
DAA04566
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