Version 5.4
Mus musculus Protein: Coq2
Summary
InnateDB Protein IDBP-183366.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Coq2
Protein Name coenzyme Q2 homolog, prenyltransferase (yeast)
Synonyms 2310002F18Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000031262
InnateDB Gene IDBG-183364 (Coq2)
Protein Structure
UniProt Annotation
Function Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002083 4-hydroxybenzoate decaprenyltransferase activity
GO:0004659 prenyltransferase activity
GO:0047293 4-hydroxybenzoate nonaprenyltransferase activity
Biological Process
GO:0006071 glycerol metabolic process
GO:0006744 ubiquinone biosynthetic process
GO:0008299 isoprenoid biosynthetic process
GO:0009058 biosynthetic process
Cellular Component
GO:0005739 mitochondrion
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Protein Structure and Domains
PDB ID MGI:1919133
InterPro IPR000537 UbiA prenyltransferase family
IPR006370 4-hydroxybenzoate polyprenyl transferase
PFAM PF01040
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q66JT7
PhosphoSite PhosphoSite-
TrEMBL D3Z296
UniProt Splice Variant
Entrez Gene 71883
UniGene
RefSeq NP_082254
MGI ID
MGI Symbol Coq2
OMIM
CCDS CCDS19465
HPRD
IMGT
EMBL AC109196 AC161510 AK009092 BC080773
GenPept AAH80773 BAB26064

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca