InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Wnt2b

Summary

InnateDB Protein

IDBP-183423.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Wnt2b

Protein Name

wingless related MMTV integration site 2b

Synonyms

Wnt13;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000029429

InnateDB Gene

IDBG-183421 (Wnt2b)

Protein Structure

UniProt Annotation

Function

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted, extracellular space, extracellular matrix.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005109	frizzled binding
GO:0005515	protein binding

Biological Process

GO:0002062	chondrocyte differentiation
GO:0007165	signal transduction
GO:0007267	cell-cell signaling
GO:0007275	multicellular organismal development
GO:0008584	male gonad development
GO:0009267	cellular response to starvation
GO:0009887	organ morphogenesis
GO:0016055	Wnt signaling pathway
GO:0021871	forebrain regionalization
GO:0030182	neuron differentiation
GO:0060070	canonical Wnt signaling pathway
GO:0060492	lung induction
GO:0060638	mesenchymal-epithelial cell signaling
GO:0071425	hematopoietic stem cell proliferation
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
GO:0090263	positive regulation of canonical Wnt signaling pathway