InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gpd1

Summary

InnateDB Protein

IDBP-183791.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gpd1

Protein Name

glycerol-3-phosphate dehydrogenase 1 (soluble)

Synonyms

AI747587; Gdc-1; Gdc1; mKIAA4010;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000023760

InnateDB Gene

IDBG-183789 (Gpd1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
GO:0004368	glycerol-3-phosphate dehydrogenase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042803	protein homodimerization activity
GO:0051287	NAD binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006072	glycerol-3-phosphate metabolic process
GO:0006094	gluconeogenesis
GO:0006116	NADH oxidation
GO:0006127	glycerophosphate shuttle
GO:0006734	NADH metabolic process
GO:0045821	positive regulation of glycolytic process
GO:0046168	glycerol-3-phosphate catabolic process
GO:0046486	glycerolipid metabolic process
GO:0055114	oxidation-reduction process
GO:0071320	cellular response to cAMP
GO:0071356	cellular response to tumor necrosis factor

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005829	cytosol
GO:0009331	glycerol-3-phosphate dehydrogenase complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:95679

InterPro

IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal
IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent
IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal
IPR017751 Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic

PFAM

PF07479
PF01210

PRINTS

PR00077

PIRSF

PIRSF000114

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt