Version 5.4
Mus musculus Protein: Fut2
Summary
InnateDB Protein IDBP-184004.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fut2
Protein Name fucosyltransferase 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000063719
InnateDB Gene IDBG-184002 (Fut2)
Protein Structure
UniProt Annotation
Function Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway.
Subcellular Localization Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Membrane-bound form in trans cisternae of Golgi. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity
GO:0008417 fucosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006486 protein glycosylation
GO:0036065 fucosylation
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:109374
InterPro IPR002516 Glycosyl transferase, family 11
PFAM PF01531
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JL27
PhosphoSite PhosphoSite-
TrEMBL Q91VF0
UniProt Splice Variant
Entrez Gene 14344
UniGene Mm.290046
RefSeq NP_061364
MGI ID
MGI Symbol Fut2
OMIM
CCDS CCDS21258
HPRD
IMGT
EMBL AB039114 AB039115 AB039116 AB039117 AB039118 AB039119 AB039120 AB039121 AF214656 AK033520 BC138534 BC145831 CH466603
GenPept AAF45146 AAI38535 AAI45832 BAB68638 BAB68639 BAB68640 BAB68641 BAB68642 BAB68643 BAB68644 BAB68645 BAC28338 EDL22881

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca