InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mapk10

Summary

InnateDB Protein

IDBP-184562.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Mapk10

Protein Name

mitogen-activated protein kinase 10

Synonyms

C230008H04Rik; JNK3; JNK3B1; JNK3B2; p493F12; p54bSAPK; SAPK(beta); Serk2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000084065

InnateDB Gene

IDBG-184558 (Mapk10)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	38 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004707	MAP kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0016773	phosphotransferase activity, alcohol group as acceptor

Biological Process

GO:0000165	MAPK cascade
GO:0006468	protein phosphorylation
GO:0009103	lipopolysaccharide biosynthetic process

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005886	plasma membrane
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:1346863

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR008351 Mitogen-activated protein (MAP) kinase, JNK
IPR010440 Lipopolysaccharide kinase
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714
PF06293

PRINTS

PR00109
PR01772

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt