InnateDB Protein
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IDBP-184904.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cd53
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Protein Name
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CD53 antigen
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Synonyms
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AI323659; Ox-44; Tspan25;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000035781
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InnateDB Gene
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IDBG-184902 (Cd53)
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Protein Structure
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Function |
Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells. {ECO:0000269PubMed:22847234}.
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Subcellular Localization |
Cell membrane {ECO:0000269PubMed:22847234}. Cell junction {ECO:0000269PubMed:22847234}. Membrane {ECO:0000269PubMed:22847234}; Multi-pass membrane protein {ECO:0000269PubMed:22847234}. Note=Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
0
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Protein-DNA |
3
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:88341
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InterPro |
IPR000301
Tetraspanin
IPR008952
Tetraspanin, EC2 domain
IPR018499
Tetraspanin/Peripherin
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PFAM |
PF00335
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PRINTS |
PR00259
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PIRSF |
PIRSF002419
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q61451
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q3U0W1
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UniProt Splice Variant |
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Entrez Gene |
12508
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UniGene |
Mm.469077
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RefSeq |
NP_031677
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MGI ID |
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MGI Symbol |
Cd53
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OMIM |
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CCDS |
CCDS17728
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HPRD |
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IMGT |
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EMBL |
AK156510
BC021310
BC052905
CH466607
X97227
Z16078
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GenPept |
AAH21310
AAH52905
BAE33740
CAA65864
CAA78892
EDL01884
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