Version 5.4
Mus musculus Protein: Tk2
Summary
InnateDB Protein IDBP-185157.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tk2
Protein Name thymidine kinase 2, mitochondrial
Synonyms AU024611; mt-TK;
Species Mus musculus
Ensembl Protein ENSMUSP00000053616
InnateDB Gene IDBG-185155 (Tk2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004137 deoxycytidine kinase activity
GO:0004797 thymidine kinase activity
GO:0005524 ATP binding
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006264 mitochondrial DNA replication
GO:0009157 deoxyribonucleoside monophosphate biosynthetic process
GO:0009262 deoxyribonucleotide metabolic process
GO:0016310 phosphorylation
GO:0032042 mitochondrial DNA metabolic process
GO:0046092 deoxycytidine metabolic process
GO:0046104 thymidine metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Protein Structure and Domains
PDB ID MGI:1913266
InterPro IPR002624 Deoxynucleoside kinase
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF01712
PRINTS
PIRSF PIRSF000705
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8BN51
UniProt Splice Variant
Entrez Gene 57813
UniGene Mm.183110
RefSeq NP_066356
MGI ID
MGI Symbol Tk2
OMIM
CCDS CCDS22573
HPRD
IMGT
EMBL AC115718 AK087557 AK154160 CH466525
GenPept BAC39926 BAE32414 EDL11202 EDL11203

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca