InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nedd1

Summary

InnateDB Protein

IDBP-185580.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nedd1

Protein Name

neural precursor cell expressed, developmentally down-regulated gene 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000020163

InnateDB Gene

IDBG-185578 (Nedd1)

Protein Structure

UniProt Annotation

Function

Required for mitosis progression. Promotes the nucleation of microtubules from the spindle (By similarity). May play an important role during the embryonic development and differentiation of the central nervous system. {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007019	microtubule depolymerization
GO:0007067	mitotic nuclear division
GO:0031109	microtubule polymerization or depolymerization
GO:0070201	regulation of establishment of protein localization

Cellular Component

GO:0000242	pericentriolar material
GO:0000922	spindle pole
GO:0000924	gamma-tubulin ring complex, centrosomal
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005814	centriole
GO:0036064	ciliary basal body
GO:0045177	apical part of cell