Version 5.4
Mus musculus Gene: Nedd1
Summary
InnateDB Gene IDBG-185578.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nedd1
Gene Name neural precursor cell expressed, developmentally down-regulated gene 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000019988
Encoded Proteins
IDBP-185580
neural precursor cell expressed, developmentally down-regulated gene 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139350:
Gene Information
Type Protein coding
Genomic Location Chromosome 10:92684746-92722420
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000020163 ENSMUSP00000020163
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007019 microtubule depolymerization
GO:0007067 mitotic nuclear division
GO:0031109 microtubule polymerization or depolymerization
GO:0070201 regulation of establishment of protein localization
Cellular Component
GO:0000242 pericentriolar material
GO:0000922 spindle pole
GO:0000924 gamma-tubulin ring complex, centrosomal
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0036064 ciliary basal body
GO:0045177 apical part of cell
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000139350
View Gene Order
ENSBTAG00000001894
Not yet available
Pathways
NETPATH
REACTOME
REACT_245720
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_240530
G2/M Transition pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_243078
Loss of Nlp from mitotic centrosomes pathway
REACT_188804
Cell Cycle pathway
REACT_246290
Recruitment of NuMA to mitotic centrosomes pathway
REACT_246508
Mitotic G2-G2/M phases pathway
REACT_244487
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_196635
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_253753
Centrosome maturation pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160315
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_15364
Loss of Nlp from mitotic centrosomes pathway
REACT_15451
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_15510
Recruitment of NuMA to mitotic centrosomes pathway
REACT_15296
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_115566
Cell Cycle pathway
REACT_15479
Centrosome maturation pathway
REACT_2203
G2/M Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_21391
Mitotic G2-G2/M phases pathway
REACT_223914
G2/M Transition pathway
REACT_215505
Cell Cycle, Mitotic pathway
REACT_205006
Loss of Nlp from mitotic centrosomes pathway
REACT_217933
Mitotic G2-G2/M phases pathway
REACT_214934
Cell Cycle pathway
REACT_214350
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_215331
Recruitment of NuMA to mitotic centrosomes pathway
REACT_224118
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_215812
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_210400
Centrosome maturation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P33215
TrEMBL
UniProt Splice Variant
Entrez Gene 17997
UniGene Mm.413109 Mm.428189
RefSeq NM_008682 XM_006513334
OMIM
CCDS CCDS24123
HPRD
IMGT
MGI ID MGI:97293
MGI Symbol Nedd1
EMBL AK010591 AK048393 AK085355 AK090040 AK153746 BC052430 BC066870 D10712
GenPept AAH52430 AAH66870 BAA01554 BAB27048 BAC33321 BAC39429 BAC41060 BAE32166
RNA Seq Atlas 17997

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca