InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gbp6

Summary

InnateDB Protein

IDBP-185860.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Gbp6

Protein Name

guanylate binding protein 6

Synonyms

AI595338; Mpa2l;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000062528

InnateDB Gene

IDBG-255448 (Gbp6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003924	GTPase activity
GO:0005525	GTP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006955	immune response
GO:0035458	cellular response to interferon-beta
GO:0042742	defense response to bacterium
GO:0042832	defense response to protozoan
GO:0044406	adhesion of symbiont to host
GO:0045087	innate immune response (InnateDB)
GO:0050830	defense response to Gram-positive bacterium
GO:0071222	cellular response to lipopolysaccharide
GO:0071346	cellular response to interferon-gamma

Cellular Component

GO:0020005	symbiont-containing vacuole membrane
GO:0031410	cytoplasmic vesicle

Protein Structure and Domains

PDB ID

MGI:2140937

InterPro

IPR003191 Guanylate-binding protein, C-terminal
IPR015894 Guanylate-binding protein, N-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF02841
PF02263

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-