InnateDB Protein
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IDBP-186304.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Serpinb7
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Protein Name
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serine (or cysteine) peptidase inhibitor, clade B, member 7
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000083896
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InnateDB Gene
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IDBG-186302 (Serpinb7)
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Protein Structure
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Function |
Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0004867
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serine-type endopeptidase inhibitor activity
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Biological Process |
GO:0010951
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negative regulation of endopeptidase activity
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GO:0030162
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regulation of proteolysis
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GO:0032914
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positive regulation of transforming growth factor beta1 production
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GO:0032967
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positive regulation of collagen biosynthetic process
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GO:0072126
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positive regulation of glomerular mesangial cell proliferation
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GO:0090362
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positive regulation of platelet-derived growth factor production
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Cellular Component |
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PDB ID |
MGI:2151053
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InterPro |
IPR023796
Serpin domain
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PFAM |
PF00079
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PRINTS |
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PIRSF |
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SMART |
SM00093
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TIGRFAMs |
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Modification |
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SwissProt |
Q9D695
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PhosphoSite |
PhosphoSite-Q9D695
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TrEMBL |
D3Z2N5
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UniProt Splice Variant |
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Entrez Gene |
116872
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UniGene |
Mm.66015
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RefSeq |
NP_081824
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MGI ID |
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MGI Symbol |
Serpinb7
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OMIM |
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CCDS |
CCDS35686
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HPRD |
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IMGT |
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EMBL |
AC129295
AC148982
AC157660
AF105328
AK014524
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GenPept |
AAL16768
BAB29410
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