InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Metap2

Summary

InnateDB Protein

IDBP-186324.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Metap2

Protein Name

methionine aminopeptidase 2

Synonyms

4930584B20Rik; A930035J23Rik; AI047573; AL024412; Amp2; AU014659; Mnpep; p67; p67eIF2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000048285

InnateDB Gene

IDBG-186322 (Metap2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004177	aminopeptidase activity
GO:0005515	protein binding
GO:0008235	metalloexopeptidase activity
GO:0046872	metal ion binding
GO:0070006	metalloaminopeptidase activity

Biological Process

GO:0006508	proteolysis
GO:0016485	protein processing
GO:0018206	peptidyl-methionine modification
GO:0031365	N-terminal protein amino acid modification
GO:0070084	protein initiator methionine removal

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

MGI:1929701

InterPro

IPR000994 Peptidase M24, structural domain
IPR001714 Peptidase M24, methionine aminopeptidase
IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2

PFAM

PF00557

PRINTS

PR00599

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O08663