InnateDB Protein
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IDBP-186396.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Vezt
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Protein Name
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vezatin, adherens junctions transmembrane protein
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000037955
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InnateDB Gene
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IDBG-186394 (Vezt)
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Protein Structure
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Function |
Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. Required for morphogenesis of the preimplantation embryo, and for the implantation process. {ECO:0000269PubMed:16199027, ECO:0000269PubMed:17452094}.
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Subcellular Localization |
Cell membrane; Multi-pass membrane protein. Cell junction, adherens junction. Nucleus. Cytoplasmic vesicle, secretory vesicle, acrosome.
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Disease Associations |
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Tissue Specificity |
Isoform 1, isoform 2 and isoform 3 are expressed in testis. In the seminiferous epithelium, present exclusively in the acrosome of spermatids (at protein level). {ECO:0000269PubMed:17379651}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
6 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2143698
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q3ZK22
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PhosphoSite |
PhosphoSite-Q3ZK22
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
215008
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UniGene |
Mm.489742
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RefSeq |
NP_766126
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MGI ID |
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MGI Symbol |
Vezt
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OMIM |
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CCDS |
CCDS36038
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HPRD |
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IMGT |
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EMBL |
AK036017
AK041354
AK042540
AY753561
AY753562
BC056428
DQ025533
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GenPept |
AAH56428
AAX12551
AAX12552
AAY87458
BAC29277
BAC30915
BAC31287
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