Version 5.4
Mus musculus Gene: Vezt
Summary
InnateDB Gene IDBG-186394.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vezt
Gene Name vezatin, adherens junctions transmembrane protein
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000036099
Encoded Proteins
IDBP-186396
vezatin, adherens junctions transmembrane protein
IDBP-400520
vezatin, adherens junctions transmembrane protein
IDBP-400518
vezatin, adherens junctions transmembrane protein
IDBP-400521
vezatin, adherens junctions transmembrane protein
IDBP-532590
vezatin, adherens junctions transmembrane protein
IDBP-533028
vezatin, adherens junctions transmembrane protein
IDBP-535952
vezatin, adherens junctions transmembrane protein
IDBP-537284
vezatin, adherens junctions transmembrane protein
IDBP-542667
vezatin, adherens junctions transmembrane protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000028203:
This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:93939165-94035817
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000047711 ENSMUSP00000037955
ENSMUST00000119818 ENSMUSP00000113715
ENSMUST00000118077 ENSMUSP00000113983
ENSMUST00000118205 ENSMUSP00000113321
ENSMUST00000148450 ENSMUSP00000121105
ENSMUST00000141241 ENSMUSP00000123575
ENSMUST00000150704 ENSMUSP00000121727
ENSMUST00000123201 ENSMUSP00000114550
ENSMUST00000150344 ENSMUSP00000122561
ENSMUST00000132735
ENSMUST00000154267
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017022 myosin binding
Biological Process
GO:0016337 single organismal cell-cell adhesion
GO:0043009 chordate embryonic development
Cellular Component
GO:0001669 acrosomal vesicle
GO:0002142 stereocilia ankle link complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000028203
View Gene Order
ENSBTAG00000014044
Not yet available
Cross-References
SwissProt Q3ZK22
TrEMBL
UniProt Splice Variant
Entrez Gene 215008
UniGene Mm.124177 Mm.256845 Mm.398492 Mm.403354 Mm.409832 Mm.414281 Mm.472222 Mm.482276 Mm.489742
RefSeq XM_006513464 XM_006513465 NM_172538 XM_006513461 XM_006513462 XM_006513463 XM_006513467
OMIM
CCDS CCDS36038
HPRD
IMGT
MGI ID MGI:2143698
MGI Symbol Vezt
EMBL AK036017 AK041354 AK042540 AY753561 AY753562 BC056428 DQ025533
GenPept AAH56428 AAX12551 AAX12552 AAY87458 BAC29277 BAC30915 BAC31287
RNA Seq Atlas 215008

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca