InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gtf2h5

Summary

InnateDB Protein

IDBP-186456.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gtf2h5

Protein Name

general transcription factor IIH, polypeptide 5

Synonyms

2700017P07Rik; 2810432H05Rik; D17Wsu155e;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000098515

InnateDB Gene

IDBG-133543 (Gtf2h5)

Protein Structure

UniProt Annotation

Function

Component of the TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Necessary for the stability of the TFIIH complex and for the presence of normal levels of TFIIH in the cell (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000182	rDNA binding

Biological Process

GO:0006289	nucleotide-excision repair
GO:0006294	nucleotide-excision repair, preincision complex assembly
GO:0006355	regulation of transcription, DNA-templated
GO:0006362	transcription elongation from RNA polymerase I promoter
GO:0006364	rRNA processing
GO:0071480	cellular response to gamma radiation