Version 5.4
Mus musculus Gene: Gtf2h5
Summary
InnateDB Gene IDBG-133543.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gtf2h5
Gene Name general transcription factor IIH, polypeptide 5
Synonyms 2700017P07Rik; 2810432H05Rik; D17Wsu155e
Species Mus musculus
Ensembl Gene ENSMUSG00000034345
Encoded Proteins
IDBP-133545
general transcription factor IIH, polypeptide 5
IDBP-186456
general transcription factor IIH, polypeptide 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
This gene encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:6079786-6086517
Strand Forward strand
Band A1
Transcripts
ENSMUST00000039487 ENSMUSP00000040355
ENSMUST00000100955 ENSMUSP00000098515
ENSMUST00000146035
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000182 rDNA binding
Biological Process
GO:0006289 nucleotide-excision repair
GO:0006294 nucleotide-excision repair, preincision complex assembly
GO:0006355 regulation of transcription, DNA-templated
GO:0006362 transcription elongation from RNA polymerase I promoter
GO:0006364 rRNA processing
GO:0071480 cellular response to gamma radiation
Cellular Component
GO:0000439 core TFIIH complex
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
null
View Gene Order
ENSBTAG00000008543
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03022
Basal transcription factors pathway
mmu03420
Nucleotide excision repair pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.303441 Mm.482208
RefSeq NM_181392 XM_006523239
OMIM
CCDS CCDS37423
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca