InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fhl3

Summary

InnateDB Protein

IDBP-186624.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fhl3

Protein Name

four and a half LIM domains 3

Synonyms

SLIM2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000040150

InnateDB Gene

IDBG-186622 (Fhl3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

In the adult, expressed at high levels in skeletal muscle and, to a lesser extent, in heart, lung, skin and kidney. During embryonic development, expressed ubiquitously at low levels. {ECO:0000269PubMed:10049693, ECO:0000269PubMed:10906474}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	29 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0030036

actin cytoskeleton organization

Cellular Component

GO:0001725	stress fiber
GO:0005634	nucleus
GO:0030018	Z disc

Protein Structure and Domains

PDB ID

MGI:1341092

InterPro

IPR001781 Zinc finger, LIM-type

PFAM

PF00412

PRINTS

PIRSF

SMART

SM00132

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9R059

PhosphoSite

PhosphoSite-Q9R059

TrEMBL

UniProt Splice Variant

Entrez Gene

14201

UniGene

Mm.331856

RefSeq

NP_034343

MGI ID

MGI Symbol

Fhl3

OMIM

CCDS

CCDS38874

HPRD

IMGT

EMBL

AF114382 AF134772 AF149826 AL606907 BC144903 BC145939

GenPept

AAD32623 AAD53231 AAF73159 AAI44904 AAI45940