Mus musculus Protein: Abcc10 | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-186818.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Abcc10 | ||||||||||||
Protein Name | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | ||||||||||||
Synonyms | |||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Protein | ENSMUSP00000038041 | ||||||||||||
InnateDB Gene | IDBG-186816 (Abcc10) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion. {ECO:0000250}. | ||||||||||||
Subcellular Localization | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000255PROSITE-ProRule:PRU00441}. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | Expressed in all tissues tested including liver, brain, heart, skeletal muscle, kidney and spleen. {ECO:0000269PubMed:11943485}. | ||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | MGI:2386976 | ||||||||||||
InterPro |
IPR001140
ABC transporter, transmembrane domain IPR003439 ABC transporter-like IPR003593 AAA+ ATPase domain IPR011527 ABC transporter type 1, transmembrane domain IPR027417 P-loop containing nucleoside triphosphate hydrolase |
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PFAM |
PF00664
PF13748 PF00005 |
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PRINTS | |||||||||||||
PIRSF | |||||||||||||
SMART |
SM00382
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TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | Q8R4P9 | ||||||||||||
PhosphoSite | PhosphoSite-Q8R4P9 | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 224814 | ||||||||||||
UniGene | |||||||||||||
RefSeq | XP_006524205 | ||||||||||||
MGI ID | |||||||||||||
MGI Symbol | Abcc10 | ||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | AF406642 AF417121 AK133240 AK170600 | ||||||||||||
GenPept | AAM18535 AAM18536 BAE21573 BAE41905 | ||||||||||||