Mus musculus Protein: Myo6
Summary
InnateDB Protein IDBP-187856.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Myo6
Protein Name myosin VI
Synonyms BC029719; sv; Tlc;
Species Mus musculus
Ensembl Protein ENSMUSP00000036181
InnateDB Gene IDBG-187852 (Myo6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 36 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0051015 actin filament binding
Biological Process
GO:0006605 protein targeting
GO:0006897 endocytosis
GO:0007268 synaptic transmission
GO:0007416 synapse assembly
GO:0007605 sensory perception of sound
GO:0007626 locomotory behavior
GO:0008152 metabolic process
GO:0014047 glutamate secretion
GO:0016358 dendrite development
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0042472 inner ear morphogenesis
GO:0042491 auditory receptor cell differentiation
GO:0042493 response to drug
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048167 regulation of synaptic plasticity
GO:0048839 inner ear development
GO:0051046 regulation of secretion
GO:0071257 cellular response to electrical stimulus
Cellular Component
GO:0001726 ruffle
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0012506 vesicle membrane
GO:0016020 membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0016459 myosin complex
GO:0016591 DNA-directed RNA polymerase II, holoenzyme
GO:0030139 endocytic vesicle
GO:0030424 axon
GO:0031941 filamentous actin
GO:0031965 nuclear membrane
GO:0032587 ruffle membrane
GO:0043025 neuronal cell body
GO:0043231 intracellular membrane-bounded organelle
GO:0043234 protein complex
GO:0045177 apical part of cell
GO:0045202 synapse
GO:0045334 clathrin-coated endocytic vesicle
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:104785
InterPro IPR001609 Myosin head, motor domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00063
PRINTS PR00193
PIRSF
SMART SM00242
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q3L1
UniProt Splice Variant
Entrez Gene 17920
UniGene Mm.417495
RefSeq NP_001034635
MGI ID
MGI Symbol Myo6
OMIM
CCDS CCDS23368
HPRD
IMGT
EMBL AC120388 AC159738
GenPept