InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Myo6

Summary

InnateDB Protein

IDBP-187858.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Myo6

Protein Name

myosin VI

Synonyms

BC029719; sv; Tlc;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000075501

InnateDB Gene

IDBG-187852 (Myo6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	36 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003774	motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0051015	actin filament binding

Biological Process

GO:0006605	protein targeting
GO:0006897	endocytosis
GO:0007268	synaptic transmission
GO:0007416	synapse assembly
GO:0007605	sensory perception of sound
GO:0007626	locomotory behavior
GO:0008152	metabolic process
GO:0014047	glutamate secretion
GO:0016358	dendrite development
GO:0042472	inner ear morphogenesis
GO:0042491	auditory receptor cell differentiation
GO:0048167	regulation of synaptic plasticity
GO:0048839	inner ear development
GO:0071257	cellular response to electrical stimulus

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0012506	vesicle membrane
GO:0016459	myosin complex
GO:0030424	axon
GO:0043025	neuronal cell body
GO:0045202	synapse
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

MGI:104785

InterPro

IPR001609 Myosin head, motor domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00063

PRINTS

PR00193

PIRSF

SMART

SM00242

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9PVU0

UniProt Splice Variant

Entrez Gene

17920

UniGene

Mm.417495

RefSeq

MGI ID

MGI Symbol

Myo6

OMIM

CCDS

HPRD

IMGT

EMBL

AC120388 AC159738

GenPept