Version 5.4
Homo sapiens Protein: KLRC4
Summary
InnateDB Protein IDBP-18877.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLRC4
Protein Name killer cell lectin-like receptor subfamily C, member 4
Synonyms NKG2-F; NKG2F;
Species Homo sapiens
Ensembl Protein ENSP00000310216
InnateDB Gene IDBG-18873 (KLRC4)
Protein Structure
UniProt Annotation
Function May play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells.
Subcellular Localization Membrane; Single-pass type II membrane protein.
Disease Associations
Tissue Specificity Natural killer cells.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006968 cellular defense response
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR016187 C-type lectin fold
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O43908
PhosphoSite PhosphoSite-O43908
TrEMBL H3BU71
UniProt Splice Variant
Entrez Gene 8302
UniGene
RefSeq NP_038459
HUGO HGNC:6377
OMIM 602893
CCDS CCDS8624
HPRD 16008
IMGT
EMBL AC022075 AF027164 AF350018 AF350019 AJ001683 AJ001686 BC017784 U96845 U96846
GenPept AAC17491 AAC51909 AAC51910 AAH17784 AAK83805 AAK83806 CAA04921 CAA04924

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca