InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hoxc8

Summary

InnateDB Protein

IDBP-189366.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hoxc8

Protein Name

homeobox C8

Synonyms

D130011F21Rik; Hox-3.1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000001703

InnateDB Gene

IDBG-189364 (Hoxc8)

Protein Structure

UniProt Annotation

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000976	transcription regulatory region sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0009952	anterior/posterior pattern specification
GO:0030182	neuron differentiation
GO:0048705	skeletal system morphogenesis