InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dpep2

Summary

InnateDB Protein

IDBP-189435.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dpep2

Protein Name

dipeptidase 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000080659

InnateDB Gene

IDBG-189431 (Dpep2)

Protein Structure

UniProt Annotation

Function

Probable metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).

Subcellular Localization

Membrane {ECO:0000269PubMed:12738806}; Lipid-anchor, GPI-anchor {ECO:0000269PubMed:12738806}.

Disease Associations

Tissue Specificity

Expressed in heart, lung, testis, spleen and skeletal muscle. {ECO:0000269PubMed:12738806}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008235	metalloexopeptidase activity
GO:0008238	exopeptidase activity
GO:0008239	dipeptidyl-peptidase activity
GO:0016805	dipeptidase activity
GO:0046872	metal ion binding

Biological Process

GO:0006508

proteolysis

Cellular Component

GO:0005575	cellular_component
GO:0031225	anchored component of membrane

Protein Structure and Domains

PDB ID

MGI:2442042

InterPro

IPR008257 Renal dipeptidase family

PFAM

PF01244

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8C255

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

319446

UniGene

Mm.488737

RefSeq

NP_795887

MGI ID

MGI Symbol

Dpep2

OMIM

CCDS

CCDS22625

HPRD

IMGT

EMBL

AF488552 AK089244 AK155417 AK170094 AK170970 AK171044 AK171122 AK171155 AK171196 AK171268 AK171503 AK171606

GenPept

AAP84986 BAC40810 BAE33255 BAE41559 BAE42149 BAE42209 BAE42264 BAE42280 BAE42306 BAE42354 BAE42494 BAE42559