Version 5.4
Mus musculus Gene: Dpep2
Summary
InnateDB Gene IDBG-189431.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dpep2
Gene Name dipeptidase 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000053687
Encoded Proteins
IDBP-189433
dipeptidase 2
IDBP-189435
dipeptidase 2
IDBP-400530
dipeptidase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167261:
DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides, including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (Habib et al., 2003 [PubMed 12738806]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:105984944-105996423
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000034373 ENSMUSP00000034373
ENSMUST00000081998 ENSMUSP00000080659
ENSMUST00000117555 ENSMUSP00000113877
ENSMUST00000150001
ENSMUST00000149057
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008235 metalloexopeptidase activity
GO:0008238 exopeptidase activity
GO:0008239 dipeptidyl-peptidase activity
GO:0016805 dipeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005575 cellular_component
GO:0031225 anchored component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000167261
View Gene Order
ENSBTAG00000039426
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150420
Synthesis of Leukotrienes (LT) and Eoxins (EX) pathway
REACT_147851
Arachidonic acid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_228214
Aflatoxin activation and detoxification pathway
REACT_111217
Metabolism pathway
REACT_13433
Biological oxidations pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8C255
TrEMBL
UniProt Splice Variant
Entrez Gene 319446
UniGene Mm.248357 Mm.488737
RefSeq XM_006531080 NM_176913 XM_006531079 XM_006531081
OMIM
CCDS CCDS22625
HPRD
IMGT
MGI ID MGI:2442042
MGI Symbol Dpep2
EMBL AF488552 AK089244 AK155417 AK170094 AK170970 AK171044 AK171122 AK171155 AK171196 AK171268 AK171503 AK171606
GenPept AAP84986 BAC40810 BAE33255 BAE41559 BAE42149 BAE42209 BAE42264 BAE42280 BAE42306 BAE42354 BAE42494 BAE42559
RNA Seq Atlas 319446

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca