InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gapdh

Summary

InnateDB Protein

IDBP-189468.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gapdh

Protein Name

glyceraldehyde-3-phosphate dehydrogenase

Synonyms

Gapd;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000073289

InnateDB Gene

IDBG-189466 (Gapdh)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.

Experimentally validated
Total	29 [view]
Protein-Protein	28 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0005515	protein binding
GO:0008017	microtubule binding
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0019899	enzyme binding
GO:0035605	peptidyl-cysteine S-nitrosylase activity
GO:0050661	NADP binding
GO:0051287	NAD binding

Biological Process

GO:0000226	microtubule cytoskeleton organization
GO:0006006	glucose metabolic process
GO:0006096	glycolytic process
GO:0017148	negative regulation of translation
GO:0035606	peptidyl-cysteine S-trans-nitrosylation
GO:0050821	protein stabilization
GO:0051402	neuron apoptotic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0015630	microtubule cytoskeleton
GO:0097452	GAIT complex

Protein Structure and Domains

PDB ID

MGI:95640

InterPro

IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I
IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain
IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family

PFAM

PF00044
PF02800

PRINTS

PR00078

PIRSF

PIRSF000149

SMART

SM00846

TIGRFAMs

Post-translational Modifications

Modification

Cross-References