InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nckap1l

Summary

InnateDB Protein

IDBP-189793.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Nckap1l

Protein Name

NCK associated protein 1 like

Synonyms

4930568P13Rik; AI463083; Hem1; Hemp1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000035400

InnateDB Gene

IDBG-189791 (Nckap1l)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030295	protein kinase activator activity
GO:0030675	Rac GTPase activator activity
GO:0032403	protein complex binding

Biological Process

GO:0001782	B cell homeostasis
GO:0002262	myeloid cell homeostasis
GO:0006461	protein complex assembly
GO:0006935	chemotaxis
GO:0030011	maintenance of cell polarity
GO:0030593	neutrophil chemotaxis
GO:0030838	positive regulation of actin filament polymerization
GO:0030866	cortical actin cytoskeleton organization
GO:0030890	positive regulation of B cell proliferation
GO:0032700	negative regulation of interleukin-17 production
GO:0032715	negative regulation of interleukin-6 production
GO:0032855	positive regulation of Rac GTPase activity
GO:0033630	positive regulation of cell adhesion mediated by integrin
GO:0035509	negative regulation of myosin-light-chain-phosphatase activity
GO:0042102	positive regulation of T cell proliferation
GO:0042327	positive regulation of phosphorylation
GO:0042493	response to drug
GO:0043029	T cell homeostasis
GO:0043066	negative regulation of apoptotic process
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation
GO:0043378	positive regulation of CD8-positive, alpha-beta T cell differentiation
GO:0045579	positive regulation of B cell differentiation
GO:0045588	positive regulation of gamma-delta T cell differentiation
GO:0045621	positive regulation of lymphocyte differentiation
GO:0045648	positive regulation of erythrocyte differentiation
GO:0045860	positive regulation of protein kinase activity
GO:0048821	erythrocyte development
GO:0050853	B cell receptor signaling pathway
GO:0060100	positive regulation of phagocytosis, engulfment
GO:0070358	actin polymerization-dependent cell motility
GO:0090023	positive regulation of neutrophil chemotaxis