Version 5.4
Homo sapiens Protein: GGT6
Summary
InnateDB Protein IDBP-18987.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GGT6
Protein Name gamma-glutamyltransferase 6
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000301395
InnateDB Gene IDBG-18985 (GGT6)
Protein Structure
UniProt Annotation
Function Cleaves glutathione conjugates. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003840 gamma-glutamyltransferase activity
GO:0036374 glutathione hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0006749 glutathione metabolic process
GO:0006750 glutathione biosynthetic process
GO:0019370 leukotriene biosynthetic process
Cellular Component
GO:0016021 integral component of membrane
GO:0031362 anchored component of external side of plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000101 Gamma-glutamyltranspeptidase
IPR029055 Nucleophile aminohydrolases, N-terminal
PFAM PF01019
PRINTS PR01210
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6P531
PhosphoSite PhosphoSite-Q6P531
TrEMBL B4DPG6
UniProt Splice Variant
Entrez Gene 124975
UniGene Hs.606318
RefSeq NP_699169
HUGO HGNC:26891
OMIM 612341
CCDS CCDS11047
HPRD 08293
IMGT
EMBL AC118754 AK074646 AK298329 AK300648 BC063111 CH471108
GenPept AAH63111 BAC11110 BAG60578 BAG62336 EAW90433

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca